Finally, how histone deacetylase inhibitors disrupt mitosis!

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Abstract

The disruption of normal mitosis by histone deacetylase inhibitors is a significant contributor to the anti-cancer effects of these drugs. However, the mechanism by which these drugs affect mitosis is poorly understood. A number of recent papers have now thrown considerable light onto how these drugs elicit this very distinctive cell cycle disruption. © 2011 Landes Bioscience.

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Gabrielli, B., Chia, K. M., & Warrener, R. (2011, August 15). Finally, how histone deacetylase inhibitors disrupt mitosis! Cell Cycle. Taylor and Francis Inc. https://doi.org/10.4161/cc.10.16.16953

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