Coloradocin, An Antibiotic From A New Actinoplanes I. Taxonomy, Fermentation and Biological Properties

Abstract

Coloradocin was discovered in a screen for anti-anaerobe activity. The producing organism was determined to be a new species of Actinoplanes, designated Actinoplanes color-adoensis sp. nov. Coloradocin inhibits Bacteroides, Clostridium and other anaerobes. It does not inhibit most aerobic bacteria but is effective against Neisseria gonorrhoeae and Haemophilus influenzae. Coloradocin has low acute toxicity. © 1987, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.