Effect of pH on neohesperidin dihydrochalcone thermostability in aqueous solutions

Abstract

The objective of this work was the evaluation of neohesperidin dihydrochalcone thermostability. For this accelerated stability study, we have used an isothermal method at three temperatures (50, 70 and 90 °C). The thermodegradation of aqueous diluted solutions of neohesperidin dihydrochalcone at various pH was studied. This degradation appeared to follow first-order kinetics and was found to be pH-dependent. In the best stability conditions (pH = 4.50), the experiments revealed an activation energy (E(a)) of 45.8 kJ mol-1 and a t(90%) of 164 days, at 20 °C.