Fractional order impedance model to estimate glucose concentration: In vitro analysis

Abstract

This paper uses tools from fractional calculus such as Cole-Cole and fractional order impedance models for estimation of glucose concentration. The measured impedance is compared with two fractional order models and the simulation results show that Cole-Cole model has limitation and cannot capture the dynamics of the simulated environment. On the other hand, the fractional order model can follow the changes in impedance for several study cases. Model parameters are correlated with various conditions of the test environment. The results of these study cases show that the fractional order model is a suitable candidate for this particular application. The hypothesis tested in this paper provides new tools for glucose concentration monitoring and measurement.