Identification of neisseria gonorrhoeae by the bruker biotyper matrix- assisted laser desorption ionization-time of flight mass spectrometry system is improved by a database extension

Abstract

Identification of Neisseria gonorrhoeae by the Bruker matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system may be affected by "B consistency categorization." A supplementary database of 17 N. gonorrhoeae main spectra was constructed. Twelve of 64 N. gonorrhoeae identifications were categorized with B consistency, which disappeared using the supplementary database. Database extension did not result in misidentification of Neisseria meningitidis.