Efficacy of Doramectin against Intestinal Nematodes and Sarcoptic Mange Mites in Naturally Infected Swine

Abstract

Endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 μg/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in Japan. By doramectin treatment, fecal egg counts were reduced >99% for Ascaris suum, Strongyloides ransomi. Oesophagostomum dentatum, and Trichuris suis; worm counts of T. suis and mite counts of Sarcoptes scabiei were reduced 90.1% on Day 21 and 99.5% on Day 28 following treatment, respectively.