Simple Synthesis of Substituted Pyrroles

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Abstract

Simple synthesis of substituted pyrroles using iodine-catalyzed and montmorillonite KSF-clay-induced modified Paal-Knorr methods has been accomplished with excellent yields. N-Substituted carbazole has also been prepared by following this method. If one of the reactants is a liquid, the reaction proceeds exceedingly well without a solvent. This method gives pyrroles with less nucleophilic multicyclic aromatic amines at room temperature.

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Banik, B. K., Samajdar, S., & Banik, I. (2004). Simple Synthesis of Substituted Pyrroles. Journal of Organic Chemistry, 69(1), 213–216. https://doi.org/10.1021/jo035200i

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