Gallium-67 SPECT-CT for the evaluation of head and neck: Preliminary study on maximum standardised uptake value in lesions, and in the parotid and submandibular glands

Abstract

Purpose: The aim of this study was to investigate the gallium-67 (67Ga) single-photon emission-computed tomography (SPECT-CT) for the evaluation of head and neck, especially maximum standardised uptake value (SUVmax) in lesions, and in the parotid and submandibular glands. Material and methods: Fourteen patients with head and neck lesions who underwent SPECT-CT at 72 hours after injection of67Ga were included in this study. The67Ga SPECT-CT parameters SUVmax were compared between the parotid glands and submandibular glands. Statistical analyses for the SUVmax were performed by Mann-Whitney U test. A p value lower than 0.05 was considered as statistically significant. Results: Of all 14 patients,67Ga SPECT-CT was positive for two cases (one malignant lymphoma and one osteomye-litis). The SUVmax for malignant lymphoma and osteomyelitis were 11.21 and 10.95, respectively. Furthermore, SUVmax for parotid glands and submandibular glands of all patients were 4.86 ± 1.89 and 4.64 ± 1.64, respectively (p = 0.694). Conclusions: This study investigated the67Ga SPECT-CT for the evaluation of head and neck, especially SUVmax of lesions, and the parotid and submandibular glands.67Ga SPECT-CT may be an effective technique for the evaluation of maxillofacial lesions.