Temporolimbic or transcallosal connections: Where is the primary lesion in schizophrenia and what is its nature?

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Abstract

A critique of the article by Bogerts on the temporolimbic system theory is presented. Schizophrenia is conceived as arising as a component of the diversity of interhemispheric (callosal) connectivity associated with the evolution of language, a process that occurred through a genetic change (the speciation event) that allowed the hemispheres to develop with a degree of independence. Language and psychosis thus have a common evolutionary origin. The anatomical changes can be considered as a boundary component of the anatomical variation that is characteristic of the species.

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Crew, T. J. (1997). Temporolimbic or transcallosal connections: Where is the primary lesion in schizophrenia and what is its nature? Schizophrenia Bulletin. Oxford University Press. https://doi.org/10.1093/schbul/23.3.521

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