Abstract
Background: There is a global perception that psychotropic utilization in children and adolescents is increasing in the US. Methods: We present prevalent estimates for all psychotropics prescribed in the US (using commercial claims from Medicare and Medicaid) to children and adolescents in 2004 (total population N = 6,808,453) and in 2014 (total population N = 11,082.260). Further we evaluated if there has been a statistically significant change in prevalence during this time period. Analyses were stratified for the 6 major drug classes, all individuals’ psychotropics (87 drugs), age and sex. Results: The prevalence of psychotropic drug prescription was 8.55% in 2004 and 9.00% in 2014 (age stratified in 2004 and 2014 toddlers: 3.08 and 2.63%, children: 8.74 and 8.73%, adolescents: 10.89% and 12.11). The prevalence for each drug class in 2004 and 2014 was: stimulants/other ADHD drugs 5.0 and 5.8%; antidepressants 2.8 and 2.7%; anxiolytic-hypnotic-sedative 2.2 and 2.3%; mood stabilizers 0.1 and 0.1%; antipsychotics 1.3 and 1.1%; and for drugs treating drug dependence 0.02 and 0.02%. Conclusions: The perception that psychotropic utilization in children and adolescents is increasing in the US, derived from the 2 to 3 fold increase seen from the mid 80’s to the mid 90’s is not valid anymore. There has been a slowdown in the increase of prescribing psychotropics. In the last 10 years, in toddlers there was a decrease in the prescription; in children there was no change; and in adolescents there was a slight increase. The prescription of antidepressants, antipsychotics and mood stabilizers has decreased overall. [Figure not available: see fulltext.].
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Lopez-Leon, S., Lopez-Gomez, M. I., Warner, B., & Ruiter-Lopez, L. (2018). Psychotropic medication in children and adolescents in the United States in the year 2004 vs 2014. DARU, Journal of Pharmaceutical Sciences, 26(1), 5–10. https://doi.org/10.1007/s40199-018-0204-6
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