Nonlinear effects in enantioselective organometallic catalysis

Abstract

In the introduction are summarized the historical developments of enantioselective organometallic catalysis. Then are discussed the problems connected with the use of enantioimpure auxiliaries, the nonlinear effects are defined and some simple mathematical models are presented. Numerous examples of positive or negative nonlinear effects are presently known, some will be presented. Nonlinear effects are useful for approaching reaction mechanisms. The asymmetric amplification can have applications in catalysis, by allowing to use a ligand which is not enantiopure. Copyright © 2007, Institut français du pétrole.