Methicillin-susceptible Staphylococcus aureus clonal complex 398: High prevalence and geographical heterogeneity in bone and joint infection and nasal carriage

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Abstract

The prevalence of clonal complex (CC) 398 methicillin-susceptible Staphylococcus aureus (MSSA) was unexpectedly high among bone and joint infections (BJIs) and nasal-colonizing isolates in France, with surprising geographical heterogeneity. With none of the major, most-known staphylococcal virulence genes, MSSA CC398 BJI was associated with lower biological inflammatory syndrome and lower treatment failure rates.

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Valour, F., Tasse, J., Trouillet-Assant, S., Rasigade, J. P., Lamy, B., Chanard, E., … Martinez, M. (2014). Methicillin-susceptible Staphylococcus aureus clonal complex 398: High prevalence and geographical heterogeneity in bone and joint infection and nasal carriage. Clinical Microbiology and Infection, 20(10), O772–O775. https://doi.org/10.1111/1469-0691.12567

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