Inflammatory bowel disease in Africa: the current landscape of pharmacological treatments and the promise of emerging innovations

Abstract

Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn’s disease, is becoming a major public health concern in Africa, particularly in cities, due to urbanization, dietary changes, and improved diagnostic tools. The present study discusses the benefits, disadvantages, and practical limitations of the pharmacological treatments for IBD patients that are currently accessible in Africa. Given the limits of conventional treatments, such as their potential for considerable side effects, high cost, and often limited accessibility, this review explores emerging new treatment approaches such as nanomedicine, personalized medicine, and the use of traditional African medicines. Highlighting the urgency for potential alternative treatments, this review explores new and developing therapeutic innovations to enhance IBD management and improve the quality of life for African patients.