Antibiotic synergy profiles of multidrug-resistant Pseudomonas aeruginosa in a nosocomial environment

Abstract

Pseudomonas aeruginosa is one of the most common nosocomial pathogens in intensive care units (ICUs), with an increased prevalence of multidrug resistance in nosocomial infections. This study aimed to determine antibiotic synergy profiles of multidrugresistantP. aeruginosa originating from ICU patients in a teaching hospital in Pretoria, South Africa. Susceptibility studies and in vitrosynergy testing were performed, utilising agar dilution and Etest methodology, respectively. Susceptibility studies revealed 94