Middle Ear Pressure Changes Over Time in Children with Down Syndrome

Abstract

Down syndrome is one of the most common genetic conditions affecting approximately 1 in every 1000 live births. There are a multitude of potential clinical manifestations associated with this condition including dysmorphic features, organic disorders such as congenital cardiac defects, gastrointestinal defects, ocular abnormalities, celiac disease and endocrine disorders along with haemato-oncological, immunological and disorders affecting the ears, nose and throat.