Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation

Abstract

Background: There is little information about the efficacy of ticlopidine plus aspirin after sirolimus-eluting stent (SES) implantation. Methods and Results: The incidence of stent thrombosis was evaluated in 1,029 patients receiving ticlopidine and aspirin after SES deployment. Clinical follow-up was obtained in 98.9% (mean follow-up 17.0±7.9 months). Early stent thrombosis was observed in 5 patients (0.49%). There was 1 case each of late (0.1%) and very late stent thrombosis (0.1%). Conclusion: Late and very late stent thrombosis in Japanese patients receiving ticlopidine and aspirin after SES deployment occurs infrequently.