Preoperative treatment of locally advanced rectal cancer

Abstract

The preoperative management of locally advanced rectal cancer has evolved over the years to establish fluoropyrimidine-based chemoradiation as the usual standard of care. With the advent of newer agents-chemotherapeutic and biologic-for treatment of colorectal cancer, their role in this setting is being evaluated as well. This review is focusing on up-to-date data and studies regarding preoperative treatment of locally advanced rectal cancer. © TOUCH MEDICAL MEDIA 2012.