Abstract
Background: Dido1 plays important roles in development. Results: Dido1 inhibition led to ES cell differentiation, and its expression promoted ES cell self-renewal. Conclusion: Dido1 participates in ES cell maintenance and forms feedback and feedforward loops with canonical ES cell factors such as Nanog and Oct4. Significance: Dido1 represents a new factor in the ES cell regulatory circuitry for maintaining self-renewal of ES cells. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.
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CITATION STYLE
Liu, Y., Kim, H., Liang, J., Lu, W., Ouyang, B., Liu, D., & Songyang, Z. (2014). The death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal. Journal of Biological Chemistry, 289(8), 4778–4786. https://doi.org/10.1074/jbc.M113.486290
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