Cross-linking of initiation factor IF3 to Escherichia coli 30S ribosomal subunit by tRANs-dlamminedichloroplatinum(II): Characterization of two cross-linking sites in 16S rRNA; a possible way of functioning for IF3

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Abstract

Summary: The Initiation factor IF3 is platinated with trans-d1anm1ne-d1chloroplat1num(II) and cross-linked to Escherichia coli 30S ribosomal subunit. Two cross-linking sites are unambiguously identified on the 16S rRNA : a major one, in the region 819-859 1n the central domain, and a minor one, 1n the region 1506-1529 1n the 3'-term1nal domain. Specific features of these sequences together with their particular location within the 30S subunit lead us to postulate a role for IF3, that conciliates topographical and functional observations made so far. © 1986 IRL Press Limited, Oxford, England.

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Ehresmann, C., Moine, H., Mougel, M., Dondon, J., Grunberg-Manago, M., Ebel, J. P., & Ehresmann, B. (1986). Cross-linking of initiation factor IF3 to Escherichia coli 30S ribosomal subunit by tRANs-dlamminedichloroplatinum(II): Characterization of two cross-linking sites in 16S rRNA; a possible way of functioning for IF3. Nucleic Acids Research, 14(12), 4803–4821. https://doi.org/10.1093/nar/14.12.4803

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