HLA antigens and antinuclear antibody titres in juvenile chronic iridocyclitis

Abstract

HLA antigen frequencies and antinuclear antibody titres were studied in 43 patients with juvenile chronic iridocyclitis. We did not detect an increased incidence of HLA-B27 in patients having chronic iridocyclitis associated with juvenile rheumatoid arthritis or in patients with 'chronic iridocyclitis in young girls'. Both groups of patients had a statistically significant increased incidence of antinuclear antibodies. However, these antibodies were detected more frequently in patients with chronic iridocyclitis associated with JRA than in patients with 'chronic iridocyclitis in young girls'.