Progress in fumagillin synthesis

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Abstract

After a brief account of the syntheses previously described in literature, several approaches of the antiangiogenic sesquiterpene fumagillin are described. Particularly, a Claisen-Ireland ring-closing metathesis strategy allowed the stereoselective preparation of several advanced intermediates in the fumagillin synthesis.

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APA

Picoul, W., Bedel, O., Haudrechy, A., & Langlois, Y. (2003). Progress in fumagillin synthesis. In Pure and Applied Chemistry (Vol. 75, pp. 235–249). Walter de Gruyter GmbH. https://doi.org/10.1351/pac200375020235

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