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The IDEAL framework for machine perfusion in liver transplantation

Nature Reviews Gastroenterology and Hepatology
DOI: 10.1038/s41575-025-01085-5
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Abstract

Liver transplantation is challenged by organ scarcity and ageing donors. Machine perfusion is a promising technique to enhance organ preservation and assessment, improving liver utilization and patient outcomes. Here, we discuss current practices in machine perfusion using the IDEAL framework and outline the steps needed to advance this technology clinically.

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van Leeuwen, O. B., Nasralla, D., Ceresa, C. D. L., Dutkowski, P., Friend, P. J., Oniscu, G. C., … Lurje, G. (2025, October 1). The IDEAL framework for machine perfusion in liver transplantation. Nature Reviews Gastroenterology and Hepatology. Nature Research. https://doi.org/10.1038/s41575-025-01085-5

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