SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)

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Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, and this disease has served as a paradigmatic model for successful rational development of targeted therapies. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. The Spanish Society of Medical Oncology (SEOM) guidelines provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers.

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Poveda, A., Martinez, V., Serrano, C., Sevilla, I., Lecumberri, M. J., de Beveridge, R. D., … Martin-Broto, J. (2016). SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016). Clinical and Translational Oncology, 18(12), 1221–1228.

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