Factors associated with corneal transplant failure

Abstract

Purpose: To analyze the clinical factors associated with corneal rejection before and after surgery. Method: In a descriptive, cross-sectional and analytical study in 130 corneal transplants, clinical factors were studied before and after surgery. Patients of both sexes, and any age were included, with a minimum follow-up of 8 months, and tectonic procedures were excluded. A descriptive and inferential analysis was conducted for the variables of gender, previous diagnoses, vascularization, trepan size, comorbidities and past medical history. P values ≤ 0.05 were considered significant. Results: A 31% rejection rate was found. A higher risk of rejection was seen in women, previous corneal transplantation or neovascularization in the recipient’s cornea and patients with glaucoma. Conclusion: It is necessary to plan new prospective and follow-up studies to assess accurately, and in a standard way, the clinical evolution of the patient who receives a cornea transplant.