Abstract
Here we describe the inhibitory activity of IQG607, pentacyano(isoniazid) ferrate(II), on isoniazid-sensitive and isoniazid-resistant strains of Mycobacterium tuberculosis, its oral toxicity, and efforts to adapt IQG607 synthesis to large chemical reactors. IQG607 represents a promising chemotherapeutic agent aiming at the inhibition of a validated and druggable molecular target.
Author supplied keywords
Cite
CITATION STYLE
Basso, L. A., Schneider, C. Z., Dos Santos, A. J. A. B., Dos Santos, A. A., Campos, M. M., Souto, A. A., & Santos, D. S. (2010). An inorganic complex that inhibits Mycobacterium tuberculosis enoyl reductase as a prototype of a new class of chemotherapeutic agents to treat tuberculosis. Journal of the Brazilian Chemical Society, 21(7), 1384–1389. https://doi.org/10.1590/S0103-50532010000700026
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
