Model-Based Design for Mispa CountX Using FPGA

Abstract

Blood analysis is a primary test for disease diagnostics. For blood tests, hematology analyzers are used. Blood samples are run on hematology analyzers. In clinical laboratories, automated hematology analyzers are the major important instrument. These analyzers are able to perform hundreds of complete blood count (CBC) per day in an automated way. Mispa CountX is India’s first indigenously built Automated 3-Part Differential Hematology Analyzer which is developed by Agappe Diagnostics Pvt. Ltd. in partnership with L&T Technology Services. It counts the blood cells based on the electrical impedance principle. It tests 60 samples per hour and gives 22 parameters (including the count of Red Blood Cells (RBC), White Blood Cells (WBC), platelets, and hemoglobin) and 3 histograms. Mispa CountX consists of a microcontroller TMS320F28377D. The project is to build an FPGA design to control the motors of Mispa CountX in the place of microcontroller TMS320F28377D. The hardware architecture of Digital Signal Processor (DSP) is not much flexible and they are programmable with software. The limitation of DSP is its fixed architecture. Various DSP applications can be implemented in a single FPGA and it offers hardware customization. For design, simulate, and validate algorithms, MATLAB is used. It automatically generates and optimizes Verilog HDL code based on the system model.