Evaluation of antioxidant and anti inflammatory activity of grape seed oil infused with silver nanoparticles an in vitro study

Abstract

Aim: The aim of the current study is to assess the anti oxidant and anti inflammatory activity of grape seed oil gel which is infused with silver nanoparticle. Materials And Methods: Materials and Methods: Grape seed oil gel infused with silver nanoparticle and the prepared gel was subjected to anti-inflammatory activity test with diclofenac sodium as standard preparation. Antioxidant properties of grape seed oil infused with silver nanoparticle was also tested with Butylatedhydroxytoulune BHT as control. Results: From the results obtained it was seen that GSO gel showed and retained both anti oxidant and anti inflammatory-activity.It was observed that the anti oxidant activity of GSO gel was lesser than that of standard at all concentration but the differences are not statistically significant (p value 0.400)whereas in the experiment to test the anti inflammatory activity of GSO gel it as seen that the percentage of inhibition at all concentration except for the highest concentration was higher than that of the standard which is statistically significant (p value 0.045). Conclusion: Grape seed extract is subjected to various changes during the synthesis of gel it is essential to check whether the properties are retained .From the results obtained it is seen that the anti oxidant and anti inflammatory activity increases as the concentration increases.