Influence of melatonin in the treatment of experimental enterobius vermicularis infection

Abstract

This study aims to realization the conceivable therapeutic of melatonin effects experimental against Enterobius vermicularis in rats. Implement this experiment during the period from August 2019 to January 2020. E.vermicularis infected with male wistar rats orally with dose 15mg/kg melatonin former of body weight for 30 day showed significantly reduction in the number of eggs and worms compared with rats orally with dose 15mg/kg melatonin accompanying and untreated rats for 30 day (P < 0.05).Histologically in intestine examined show increase numbers of leucocytes produce, necrosis significant scatter and reduction this parasite of tissue in rats treated with melatonin. This results show influence of melatonin in the control on Enterobiosis and suggestion that this drug usefulness in Enterobius vermicularis infection therapy.