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Screening Veterans for Syphilis: Implementation of the Reverse Sequence Algorithm

Clinical Infectious Diseases (2017) 65(11) 1930-1933
DOI: 10.1093/cid/cix679
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Abstract

We evaluated the syphilis reverse sequence algorithm (RSA) in a Veteran Affairs facility, finding 5.5% reactive Treponema pallidum enzyme immunoassay (EIA) tests. In a subset of EIA+/VDRL-/TP-PA+ cases, 48% were previously treated. Of veterans with unknown/no prior therapy, only 45% had documentation of subsequent treatment, suggesting suboptimal interpretation of RSA results.

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Clement, M. E., Hammouda, A., Park, L. P., Maxwell, J., Samoff, E., Seña, A. C., & Joyce, M. (2017). Screening Veterans for Syphilis: Implementation of the Reverse Sequence Algorithm. Clinical Infectious Diseases, 65(11), 1930–1933. https://doi.org/10.1093/cid/cix679

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