Ruthenium red and lanthanum nitrate a possible tracer and negative stain for scrapie "particles"?

Abstract

The cucumber- or sausage-shaped particles described before in scrapie rat and natural scrapie sheep are also found in scrapie mouse with the use of ruthenium red and lanthanum nitrate. It is suggested that they have a nucleic acid core surrounded by a coat of acid polysaccharide. The plasma membranes are pair of unit membranes. © 1974 Springer-Verlag.