Comparative Accuracy Evaluation of a Blood Glucose Meter With Novel Hematocrit Correction Technology, With Three Currently Used Commercially Available Blood Glucose Monitoring Systems

Abstract

Hematocrit is known to influence glucose values obtained on some blood glucose meters, with bias observed especially at low and high hematocrit levels. We evaluated the performance of a meter with hematocrit correction technology alongside 3 other commercially available meters. Capillary blood samples from 100 subjects were analyzed in duplicate and compared to the plasma values obtained by reference laboratory analyzer. Bias, error grid, and sensitivity to hematocrit analyses were performed for each meter. Average percentage bias was similar for all meters, however the evaluated meter performed best with respect to error grid analysis, with 100% of values falling within the “no effect on clinical action” and “no risk” categories and did not display any hematocrit associated bias.