Cardioprotective Potential of Baicalein: A Short Review of In Vitro and In Vivo Studies

Abstract

Many plant-derived natural components have been recognized as effective in the treatment of human diseases. Baicalein (5,6,7-trihydroxyflavone) is one of the primary active components of Scutellaria species, and is well known ingredient in traditional Chinese medicine (TCM) and oriental medicine. Numerous studies have reported that baicalein possesses multiple pharmacological functions, such as anticancer, antioxidant, anti-inflammatory, neuroprotective, hepatoprotective, and antimicrobial properties. The cardioprotective effect of baicalein has been proved in several cell culture and small animal models. This review addresses the recent findings of cardioprotective potentials of baicalein in vitro and in vivo