Inhibition of Human Breast cancer cells proliferation by Graviola crude extract

Abstract

Rapid increases in cancer and human death cases, as well as the fatal side effects of chemotherapy, have forced the seek new safer anti-cancer drugs. Therefore, the current study was conducted to study the effect of Graviola leaf extract on the proliferation of human breast cancer (MCF-7) cell lines. MCF-7 cells were cultured and a Neutral red uptake assay was done to estimate the effect of Graviola extract on MCF-7 cells' proliferation. Treatment with different concentrations of Graviola leaf extract inhibited the proliferation of MCF-7 cells in a concentration-dependent manner. Conclusion: Graviola leaf extract has a promising inhibitory effect against the proliferation of MCF-7 cells.