Journal ArticleOPEN ACCESS

Advances in the Genetics of Familial Renal Cancer

  • Morrison P
  • Donnelly D
  • Atkinson A
  • et al.
The Oncologist (2010) 15(6) 532-538
DOI: 10.1634/theoncologist.2010-0023
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Abstract

We discuss recent advances in the diagnosis and management of renal cell cancer (RCC) given the enhanced molecular genetics knowledge in this area. A number of hereditary renal cancer syndromes have been described, including von Hippel-Lindau disease, Birt-Hogg-Dubé syndrome, hereditary leiomyomatosis/RCC syndrome, and hereditary papillary renal cancer. Early molecular diagnosis now facilitates the management and prevention of RCC in families. Recommendations for screening in families are discussed. © AlphaMed Press.

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Morrison, P. J., Donnelly, D. E., Atkinson, A. B., & Maxwell, A. P. (2010). Advances in the Genetics of Familial Renal Cancer. The Oncologist, 15(6), 532–538. https://doi.org/10.1634/theoncologist.2010-0023

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