A new in situ enhancement of the hydroxyapatite surface by Tyramine: Preparation and interfacial properties

Abstract

The grafting of biogenic monoamine can provide an effective route to modify the surface properties of apatite materials. This study presents the modification of the hydroxyapatite surface by Tyramine prepared by hydrothermal reaction. The nanoparticles of Tyramine grafted hydroxyapatite were characterized by x-ray diffraction, infrared spectroscopy, solid-state NMR spectroscopy, thermal analysis, TEM microscopy, and measurements of the specific surface area (SBET). In situ grafting of Tyramine onto the HAp surface reduces crystal growth through the formation of organic-inorganic hybrid nanoparticles, thereby developing a multifunctional surface, thus providing a good compatibility with surface interaction for cell-modified HAp. To better illustrate the surface properties of the prepared biomaterials, the interaction of methyl-orange with the modified HAp was studied using a modified method developed within the framework of this work. Effect of the grafting rate on the adsorption performance was examined. The adsorption kinetics were well described by a second order model, which is remarkably influenced by the Tyramine grafting rate.