Clinical and infection control implications of clostridium difficile infection with negative enzyme immunoassay for toxin

Dubert M. Guerrero; Christina Chou; Lucy A. Jury; Michelle M. Nerandzic; Jennifer C. Cadnum; Curtis J. Donskey

Journal ArticleOPEN ACCESS

Clinical and infection control implications of clostridium difficile infection with negative enzyme immunoassay for toxin

Clinical Infectious Diseases (2011) 53(3) 287-290

DOI: 10.1093/cid/cir361

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Abstract

In a prospective study of 132 patients with a diagnosis of Clostridium difficile infection (CDI) by polymerase chain reaction, 43 (32%) had enzyme immunoassay (EIA) results negative for toxin. EIA-negative patients with CDI did not differ in clinical presentation from EIA-positive patients and presented a similar risk for transmission of spores. © 2011 The Author Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved.

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Guerrero, D. M., Chou, C., Jury, L. A., Nerandzic, M. M., Cadnum, J. C., & Donskey, C. J. (2011). Clinical and infection control implications of clostridium difficile infection with negative enzyme immunoassay for toxin. Clinical Infectious Diseases, 53(3), 287–290. https://doi.org/10.1093/cid/cir361

Clinical and infection control implications of clostridium difficile infection with negative enzyme immunoassay for toxin

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