Precautionary Ellagic Acid Treatment Ameliorates Chronically Administered Scopolamine Induced Alzheimer's Type Memory and Cognitive Dysfunctions in Rats

Abstract

Abstract: Traditionally, herbal plants are widely and frequently used as medicines for curing and anticipating of various diseases and ailments. Plants belonging to family Burseraceae are very important and widely used as therapeutic agents. From ancient times, Boswellia serrata (BS), belonging to family Burseraceae is well known as frankincense (Jesus gifted herb). Resins are main constituents of Burseraceae family, β-boswellic acid, acteyl-β-boswellic acid, 11-keto-β-boswellic acid, acetyl-11-keto-β-boswellic acid, α-boswellic acid, acetyl-α-boswellic acid are few among several medicinally important constituents of BS generally used for curing various ailments such as rheumatism, skin diseases, cough, diarrhea, constipation, flatulence, stomachic, carminative, diuretic and neurodegenerative. Bench work has revealed numerous pharmacological activities of BS viz., anti-inflammatory, anti-oxidant, anti-ulcer, anti-arthritic, anti-asthmatic, anti-artherosclerotic, anti-cancer, anti-diarrhoeal, hepatoprotective, anti-microbial, anti-hyperglycemic, wound healing, diuretic and analgesic. However, few activities like wound healing, hypoglycemic property need intense and focused research for confirmed results. In this review, we have widely discussed chemical constituents and medicinal potential of BS.