Pharmaceutico-chemical analysis of kharjoorasava and evaluation of its clinical efficacy in Pandu Roga

Abstract

The use of fermented products as food and drinks using various raw materials for both intoxicating and therapeutic purpose has been in practice since time immemorial. In due course of time, it was absorbed into Ayurveda and the Acharyas developed the procedure called sandhana kalpana. Shortage of the genuine raw materials is an arising problem in the pharmaceutical industry in the present era. So it is very important to choose medicines containing lesser number of ingredients which are having good clinical efficacy, from the innumerable formulations told in Ayurveda. Pharmaceutical study includes pharmaceutical preparation of kharjoorasava and documenting the steps involved in the procedure. Analytical study emphasized on developing analytical standards of the final product using various chemical analyses. In clinical Study 30 patients fulfilling the inclusion criteria were selected randomly and medicine was given for 28 days at the dosage of 25 ml. Follow up was taken on 56th day of commencement of the treatment. After treatment, the trial drug showed significant action on pandu roga, with the symptoms like Panduta, Dourbalya, Hridspandana, Bhrama, Shunakshikuta, Rukshata, Swasa, Aruchi, Pindikodweshtana, Jwara and decreased Hb levels.