Absence of association between a functional polymorphism of ALOX15 gene and infertility in endometriosis

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Abstract

The aim of the present study, involving 463 women of reproductive age, was to evaluate for the first time the relationship between endometriosis, endometriosis-related infertility, and a recently described functional polymorphism in the ALOX15 gene, reported to be essential for implantation. In our study population, ALOX15 -292 C/T was not correlated either with the risk of developing an endometriosis or with the risk of infertility. © 2009 American Society for Reproductive Medicine.

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Borghese, B., Gayet, V., Chiche, J. D., Vernerey, D., de Ziegler, D., Bonaiti-Pellié, C., & Chapron, C. (2009). Absence of association between a functional polymorphism of ALOX15 gene and infertility in endometriosis. Fertility and Sterility, 91(4 SUPPL.), 1414–1416. https://doi.org/10.1016/j.fertnstert.2008.05.039

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