Factores asociados a la mortalidad por tuberculosis en indígenas en Paraguay, 2014 a 2019

Abstract

Background: The estimated tuberculosis (TB) mortality rate in Paraguay in 2019 was 3.9 per 100,000 people. Indigenous communities are at high risk for TB. Aim: To determine the factors associated with mortality in indigenous people with a diagnosis of TB in Paraguay, 2014-2019. Methods: A retrospective observational study was done. sociodemographic data and risk factors data from the National TB Program of Paraguay between the years 2014 to 2019 were used. Results: A total of 2,210 indigenous people with a diagnosis of TB were included, 53,8% were male, between 20 to 39 (32.3%) and 0 to 19 years old (30.2%), the localization of TBC was majority pulmonary (92.3%). During 2014 to 2019 the were 217 deaths (9.8%). The factors associated to mortality in TB patients were the age (ad OR = 13.95; CI: 7.07-27.55 older than 80 years), (ad OR = 4.20; CI: 2.59-6.82 older than 60 years), and (ad OR = 3.30; CI: 2.06-5.2840 to 59 years), HIV co-infection (ad OR = 7.07; CI 3.74-13.87), and localization of TB (ad OR = 3.60; CI: 1.88-6.90 for disseminated TB). Conclusion: Older age, HIV co-infection and disseminated localization of TBC are associated with a higher risk of death in indigenous people with TB.