CHEMICAL CONSTITUENTS AND PRELIMINARY ANTHELMINTIC ACTIVITY OF FICUS PLATYPHYLLA (DEL)

Abstract

A phytochemical study of Ficus platyphylla Del cultivated in Egypt is presented. A 7-methoxy coymarin (herniarin), two unidentified coumarins, a- and b-amyrin, ceryl alcohol, b-sitosterol, ursolic acid; in addition, chrysoeriol, rutin and unknown flavonoid aglycone were isolated. The organic acids content of the fruits was identified. The amino acids as well as the curdling effect and proteolytic activity of the latex were investigated. The anthelmintic activity of the 40% ethanolic extract of the fruits was studied in-vivo. A pronounced decreae in number of Ascaris worms in relation to the injected embryonated eggs was noticed in treated Fayomi chickens. This effect increases markedly with the increase of the given dose.