Sakyomicins a, b, c and d: New quinone-type antibiotics produced by a strain of nocardia taxonomy, production, isolation and biological properties

Abstract

Actinomycete strain M-53, a new soil isolate, was found to produce four quinone-type antibiotics. Antibiotic sakyomicin components A, B, C and D were isolated from the fermentation broth of strain M-53 by XAD-2 column chromatography, silica gel column chromatography and Sephadex LH-20 column chromatography. The components are active against Gram-positive bacteria. Strain M-53 was identified as a strain of genus Nocardia. © 1984, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.