Poor differentiation is an important hallmark of cancer cells, and differentiation therapy holds great promise for cancer treatment. The restoration of IkB kinase α (IKKα) leads to the differentiation of nasopharyngeal carcinoma cells with reduced tumorigenicity. The findings by Yan et al. validate the polycomb protein enhancer of zeste homologue 2 (EZH2) as a target for intervention.
CITATION STYLE
Yan, M., & Liu, Q. (2016). Differentiation therapy: A promising strategy for cancer treatment. Chinese Journal of Cancer, 35(1). https://doi.org/10.1186/s40880-015-0059-x
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