Copper(I)-Anchoring Covalent Organic Polymer for Heterogeneous CuAAC Reaction without Reducing Agents and Copper Leaching

Abstract

A novel copper(I)-anchored covalent organic polymer (Cu+@COP) is presented as a robust, heterogeneous catalyst for copper-catalyzed azide–alkyne cycloaddition (CuAAC), operating without the need for external reducing agents or observable copper leaching. Cu+stabilization is achieved via multidentate N,O-ligand coordination within the polymer matrix, enabling high catalytic efficiency (up to 95% yield) and recyclability. Structural, spectroscopic, and ICP-OES analyses confirm Cu presence, offering an alternative to traditional CuAAC protocols. This system combines operational simplicity, reduced waste, and green chemistry principles, positioning Cu+@COP as a practical catalyst for applications in synthetic and materials chemistry.