Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol

Abstract

An electrochemical sensor for paracetamol is executed by using conductive MOF (NiCu-CAT), which is synthesized by 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) ligand. The utility of this 2D NiCu-CAT is measured by the detection of paracetamol, p-stacking within the MOF layers is essential to achieve high electrical conductivity, redox activity, and catalytic activity. In particular, NiCu-CAT demonstrated detection Limit of determination near 5μM for paracetamol through a wide concentration range (5–190 μM). The NiCu-CAT/GCE exhibits excellent reproducibility, stability, and interference for paracetamol.