Electrospun curcumin-loaded polymer nanofibers: solution recipes, process parameters, properties, and biological activities

Abstract

Nanofibers loaded with biologically active compounds have attracted attention in recent years due to the controlled properties and targeted action. Curcumin, being the known regulator of many signaling pathways, and demonstrating many types of biological activities, most of them due to its antioxidant and anti-inflammatory effects, has attracted great attention for its increasing biological effects. In this review all known data about the electrospun curcumin-loaded fibers based on a polymer matrix have been collected and analyzed. In addition to the consideration of solution formulations and technological parameter dependencies, the curcumin release and biological effects of drug delivery systems are considered in detail.