The natural history of type 1A diabetes

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Abstract

We can now predict the development of Type 1A (Immune Mediated) diabetes primarily through the determination of four biochemically characterized islet autoantibodies [insulin, GAD65, IA-2 (ICA512) and (Znt8)]. Prediction is possible because beta-cell destruction is chronically progressive and very slow in most, but not all individuals. We can also prevent type 1A diabetes in animal models and a major goal is the prevention of type 1A diabetes in man with multiple clinical trials underway. Copyright© ABE&M.

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Eisenbarth, G. S., & Jeffrey, J. (2008, March). The natural history of type 1A diabetes. Arquivos Brasileiros de Endocrinologia e Metabologia. https://doi.org/10.1590/S0004-27302008000200002

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