Flavonoids from the herb of bidens pilosa L

Abstract

Chemical constituents of the whole herb of Bidens pilosa L. were investigated. By using various column chromatography (CC) and spectroscopic methods, 13 flavonoids were isolated and identified as follows: 2'-hydroxy-4,4'-dimethoxy-chalcone (1), isoliquiritigenin (2), 3,2',4'-trihydroxy-4-methoxy-chalcone (3), licochalcone A (4), 4'-O-β-D-glucopyranosyl-2', 3-dihydroxy4methoxy-chalcone (5), butein (6), apigenin (7), luteolin (8), diosmetin (9), chrysoeriol (10), 3,5,6,7,3',4',5'-heptamethoxyflavone (11), 7-O-βD-glucopyranosyl-5,3'-dihydroxy-3,6,4'-trimethoxyflavone (12), and sulfuretin (13). Compounds 1-5, 9, 11 were obtained from the genus Bidens for the first time. © 2011 Journal of Chinese Pharmaceutical Sciences, School of Pharmaceutical Sciences, Peking University.