Pipelle endometrial sampling vs dilatation and curettage in abnormal uterine bleeding

Abstract

Aim to ascertain if aspiration endometrial sampling can replace conventional dilatation and curettage for histopathological evaluation in abnormal uterine bleeding. Materials and Methods: The present study was a prospective, observational, comparative study conducted at Tata Main Hospital from 1st November 2015 to 31st October 2016. Sample size was calculated as 200. Data was analyzed using SPSS 22 version software. Sensitivity, pecificity, NPV, PPV and accuracy of histopathological diagnosis of pipelle will be computed taking DNC as the standard. Result: The global sensitivity of pipelle endometrial biopsy is 90.72%, specificity is 100%, NPV is 25%, 100% is PPV. Conclusion: The accuracy for histopathological diagnosis is good if sample is adequate, hence it can be used as a first line method for endometrial sampling. Additional diagnostic methods need to be applied if sample obtained is inadequate for histological examination or if insertion fails.