Risk assessment and persistence evaluation of Spiromesifen 240 SC on cucumber in India

Abstract

Spiromesifen 240 SC was applied @ 144 g a.i./ha (T1) and 288 g a.i./ha (T2) on cucumber twice in ten days interval under randomised block designed field experiment. Cucumber fruit samples were collected at different day's interval, subjected to extraction and clean-up by modified QuEChERS technique and residue of spiromesifen was quantified by GC-ECD. Initial deposits of spiromesifen in cucumber fruit were 0.43 and 0.80 mg/kg for T1 and T2, respectively. No residue detected in harvest samples above LOQ. Half-life (t1/2) of spiromesifen were calculated 2.12 and 2.19 days and safe waiting period (TMRL) were determined 5.83 and 8.11 days for T1 and T2, respectively. TMRC was much lesser than MPI even though initial deposit was considered. The % ADI values were 8.82% and 16.52% at highest residual deposits on 0 day for single and double dose respectively indicates safety for human consumption.